The condition, which is exceedingly rare, can lead to amputation of the penis and testicles in men. SGLT2 inhibitors are some of the most widely-used diabetes drugs in America. The class includes Invokana and Invokamet, medications manufactured by Janssen Pharmaceuticals, along with Jardiance and Farxiga. Over recent decades, the drugs have been linked to a host of severe side effects, including kidney disorders and limb amputations. Of the 12 cases identified from the medical literature, 5 of whom were women. How Common Is The Disease?
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Blood culture to check for bacteria An incision of the skin to see if pus is present Skin tissue biopsy and culture Treatment Treatment is needed right away to prevent death. You'll likely need to stay in the hospital. Powerful antibiotics are given through a vein IV Surgery to drain the sore and remove dead tissue Special medicines called donor immunoglobulins antibodies to help fight the infection in some cases Other treatments may include: Skin grafts after the infection goes away to help your skin heal and look better Amputation if the disease spreads through an arm or leg Hundred percent oxygen at high pressure hyperbaric oxygen therapy for certain types of bacterial infections Outlook Prognosis How well you do depends on: Your overall health especially if you have diabetes How fast you were diagnosed and how quickly you received treatment The type of bacteria causing the infection How quickly the infection spreads How well treatment works This disease commonly causes scarring and skin deformity. Death can occur rapidly without proper treatment. Possible Complications Complications that may result from this condition include:
How is necrotizing fasciitis diagnosed? In addition to looking at your skin, your doctor may perform several tests to diagnose this condition. They may take a biopsy , which is a small sample of the affected skin tissue for examination. Blood tests can show if your muscles have been damaged.
Treatment[ edit ] Surgical debridement cutting away affected tissue is the mainstay of treatment for necrotizing fasciitis. Early medical treatment is often presumptive; thus, antibiotics should be started as soon as this condition is suspected. Tissue cultures rather than wound swabs are taken to determine appropriate antibiotic coverage, and antibiotics may be changed in light of results. Besides blood pressure control and hydration, support should be initiated for those with unstable vital signs and low urine output. Surgical incisions often extend beyond the areas of induration the hardened tissue to remove the damaged blood vessels that are responsible for the induration.